Image Interpretation: Normal radial nerve at the antecubital fossa, physiologic branching into superficial and deep radial branches, and then multifocal, markedly hypoechoic focal enlargement of the Posterior Interosseous Nerve (PIN) within the radial tunnel. The two enlarged foci are immediately superficial to the proximal radius ORIF plate, with a short intervening segment of near normal caliber nerve giving a "dumbbell" appearance. Findings correlate with posterior interosseous neuropathy/neuroma in continuity in the setting of prior trauma and hardware proximity. This is consistent with prior EMG showing denervation in PIN innervated muscles and preserved sensation.
Teaching Pearl: A triad of sonographic findings, as seen in this case, are classically present with a true PIN syndrome that clinically manifests with motor weakness of PIN-innervated muscles. This triad includes increased anteroposterior nerve diameter measured at the arcade of Frohse, echotexture changes of the PIN, and caliber changes of the PIN throughout its course. While there are no established values for abnormal cross-sectional area for the PIN, the contralateral side can be used for reference as a comparaison. One study (Dietz et al., 2016) cited a 53% to 339% enlargement compared to the contralateral side in patients with electrodiagnostic evidence of PIN syndrome.
References:
Dietz AR, Bucelli RC, Pestronk A, Zaidman CM. Nerve ultrasound identifies abnormalities in the posterior interosseous nerve in patients with proximal radial neuropathies. Muscle Nerve. 2016 Mar;53(3):379-83.
Djurdjevic T, Loizides A, Löscher W, Gruber H, Plaikner M, Peer S. High resolution ultrasound in posterior interosseous nerve syndrome. Muscle Nerve. 2014 Jan;49(1):35-9. doi: 10.1002/mus.23867. Epub 2013 Sep 20. PMID: 23559033.