Image Interpretation: First dorsal extensor compartment (abductor pollicis longus and extensor pollicis brevis) with a thickened, hypoechoic extensor retinaculum and evidence of tenosynovial fluid consistent with De Quervain Tenosynovitis.
Teaching Pearl: De Quervain tenosynovitis affects the abductor pollicis longus and extensor pollicis brevis in the first dorsal extensor compartment at the radial styloid. Ultrasound may show retinacular thickening, tendon sheath fluid, synovial hypertrophy, Doppler hyperemia, and impaired tendon gliding.
It can also be beneficial to look for a septated first compartment or separate EPB subcompartment, because this can explain incomplete response to injection if medication does not reach both tendon compartments. Ultrasound can also help to distinguish De Quervain disease from alternative causes of radial-sided dorsal wrist pain such as intersection syndrome, thumb CMC arthritis, a symptomatic ganglion, or superficial radial neuritis.
References:
1. Lee KH, Kang CN, Lee BG, Jung WS, Kim DY, Lee CH. Ultrasonographic evaluation of the first extensor compartment of the wrist in de Quervain’s disease. J Orthop Sci. 2014;19(1):49-54. doi:10.1007/s00776-013-0481-3
2. De Keating-Hart E, Touchais S, Kerjean Y, Ardouin L, Le Goff B. Presence of an intracompartmental septum detected by ultrasound is associated with the failure of ultrasound-guided steroid injection in de Quervain’s syndrome. J Hand Surg Eur Vol. 2016;41(2):212-219. doi:10.1177/1753193415611414
3. Lee YS, Choi WS, Baek SH, Kang H, Lee CH. Comparative analysis of ultrasound and surgical findings in anatomical variations of de Quervain’s disease. Clin Orthop Surg. 2025;17(2):308-316. doi:10.4055/cios24127