Image Interpretation: At the level of the fibular head there is a well-circumscribed hypoechoic mass resulting in loss of the normal striation pattern of the common fibular nerve. The mass measured roughly 0.95 x 0.8 x 0.5 cm and was not compressible. There was no doppler signal or acoustic shadow. This was seen in both sagittal and transverse planes.
Teaching Pearl: Peroneal neuropathy is the most common lower extremity peripheral neuropathy. Most cases are caused by external compression or direct trauma to the nerve. Rarely, peripheral neuropathy can be caused by intraneural ganglia. An intraneural ganglion cyst is a benign mucinous cyst originating from the epineurium of a peripheral nerve. These cysts have been documented in several peripheral nerves but are most found at the common peroneal nerve. Symptoms range from burning pain, tingling or numbness of the anterolateral leg from just below the fibular head to the dorsal aspect of the foot, to sensory loss to the dorsum of the foot and, in prolonged or severe cases, weakness in ankle dorsiflexion, foot eversion, and great toe extension. Diagnosis is typically based on MRI. Surgical treatment is the first-choice treatment for a peroneal intraneural ganglion. Conservative treatment is not recommended because, when performed early, surgical treatment is highly successful. Ultrasound offers a less expensive and non-invasive option to guide treatment.