Image Interpretation: The median nerve is hypoechoic and enlarged in appearance, measuring approximately 17mm2 at the wrist crease. The flexor tendons are normal in appearance without tear or evidence of tenosynovitis. Normal appearing Guyon's canal. Ultrasound findings are compatible with a clinical diagnosis of carpal tunnel syndrome.
Teaching Pearl: Median nerve ultrasound is one evidence-based diagnostic tool for carpal tunnel syndrome. The most common measurement is median nerve cross-sectional area at the carpal tunnel inlet, with supportive findings including nerve hypoechogenicity, nerve flattening in the tunnel, reduced nerve mobility, and palmar bowing of the flexor retinaculum.
Ultrasound can be both diagnostic and etiologic. It can identify tenosynovitis, a ganglion, a persistent median artery, masses, an anomalous muscle, or marked nerve enlargement suggesting atypical disease. Results should be interpreted with symptoms, physical examination, and electrodiagnostic testing when needed.
References:
1. Cartwright MS, Hobson-Webb LD, Boon AJ, et al. Evidence-based guideline: neuromuscular ultrasound for the diagnosis of carpal tunnel syndrome. Muscle Nerve. 2012;46(2):287-293. doi:10.1002/mus.23389
2. Pelosi L, Arányi Z, Beekman R, et al. Expert consensus on the combined investigation of carpal tunnel syndrome with electrodiagnostic tests and neuromuscular ultrasound. Clin Neurophysiol. 2022;135:107-116. doi:10.1016/j.clinph.2021.12.012
3. Bianchi S, Hoffman DF, Tamborrini G, Poletti PA. Ultrasound findings in less frequent causes of carpal tunnel syndrome. J Ultrasound Med. 2020;39(12):2469-2482. doi:10.1002/jum.15349